Ndumele CE, Rangaswami J, Chow SL, Neeland IJ, Tuttle KR, Khan SS, Coresh J, Mathew RO, Baker-Smith CM, Carnethon MR, Despres JP, Ho JE, Joseph JJ, Kernan WN, Khera A, Kosiborod MN, Lekavich CL, Lewis EF, Lo KB, Ozkan B, Palaniappan LP, Patel SS, Pencina MJ, Powell-Wiley TM, Sperling LS, Virani SS, Wright JT, Rajgopal Singh R, Elkind MSV
Growing partisanship and ideological polarisation within and between both major parties in Congress will make consensus on federal spending priorities hard to achieve
The metabolic improvements from GLP-1 medications (weight loss, improved insulin sensitivity, reduced inflammation) combined with the cardiovascular benefits of estrogen replacement create a favorable risk profile
The combination therapy could be ideal for T2D with a combined phenotype, such as obese with HF of ischemic origin and very high risk of new CV events
While studies have shown increased c-Fos activity throughout the brain following administration of GLP-1 receptor agonists, further investigation revealed that this activation often does not correlate with the presence of GLP-1 receptors in those same neurons