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We show that the model reproduces precisely the empirically observed decline in liver GSH during starvation, as well as its diurnal variation under normal fed conditions

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In senescence-accelerated murine models, TERT activation by Epithalon correlates with increased median and maximal lifespan, reduced incidence of cytogenetic anomalies in bone marrow metaphases, and improved resistance to oxidative and genotoxic stress 2,4