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Of the remaining 20 phenotypes, PNKP showed a negative effect on phenotypes related to body impedance (e.g., whole-body and limb impedance), suggesting that higher PNKP expression may be associated with lower impedance (i.e., higher muscle mass and lower fat content)

In recent years, the skincare industry has witnessed a surge in the popularity of supplements like glutathione, touted for their potential to improve skin complexion and combat various skin issues

R747W is a mutant phenotype with loss-of-function of the gene encoding iPLA2, which reduces the hydrolytic activity of 15-HpETE-PE, and increases the content of 15-HpETE-PE in cells, and increases the sensitivity to ferroptosis compared with the wild type

Metabolic characterization of imatinib-resistant BCR-ABL T315I chronic myeloid leukemia cells indicates down-regulation of glycolytic pathway and low ROS production