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Why to test MTHFR mutations are prevalent in the general population, and may play a significant role in cancer, birth defects, cardiovascular disease, fibromyalgia, and other health issues

The study was approved by the West MidlandsSolihull Research Ethics Committee (17/WM/0179) and all subjects provided written informed consent according to Declaration of Helsinki principles

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Production of atherogenic trimethylamine N-oxide (TMAO) from carnitine is a gut microbiota-directed pathway and varies widely among individuals

Targeted lab assessment should be considered when weight loss is rapid or symptoms emerge