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Kelley RK, Cheng A-L, Braiteh FS, Park J-W, Benzaghou F, Milwee S, Borgman A, El-Khoueiry AB, Kayali ZK, Zhu AX, Rimassa L

Ghrelin the endogenous ligand for GHS-R1a is known as the hunger hormone, and GHS-R1a agonism stimulates appetite through hypothalamic NPY/AgRP neuron activation

Your appetite is reduced, so you are taking in less water from food and drinks

GLP-1 pills may be a good non-surgical option for some patients, but gastric sleeve surgery often produces more durable long-term weight loss, especially for patients with higher BMI levels or obesity-related health conditions

If youre taking Wegovy and feel unsure about your progress, your GP can review your treatment and make adjustments if needed