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This speculation is supported by the evidence that the residues involved in the interaction with MAX2 are conserved between GR24-binding HTLs and the KAR 1 -binding HTLs (Supplementary Fig

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2 Department of Biological Science, Purdue University, West Lafayette, IN, USA *These authors contributed equally to this work Abstract: Glutathione S-transferase (GST) is a Phase II metabolic enzyme that is an important facilitator of cellular detoxification

Furthermore, the indole evoked a concentration-dependent increase in ROS production in the mitochondria and in the cytosol