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Methods We conducted a single-center observational cohort study that included adult patients with IBD who were started on GLP-1-based therapy (semaglutide or tirzepatide) for weight loss from January 2021 to April 2024

Dehydration may cause kidney failure, which can lead to the need for dialysis

This may be attributed to their roles in supporting mitochondrial function and reducing oxidative stress, which can contribute to fatigue

Positive psychological effects : Weight loss with GLP-1 can lead to improved self-esteem and mental health due to better body image

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