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[29] The cells can survive freezing under certain conditions, with viability decreasing over time

The rd1 mouse is a common animal model used to study RP in which the expression of over 60 genes, related to proliferation, apoptosis, and transcription, is modified via a mutation in the phosphodiesterase-6 gene, which affects the metabolism of cyclic guanosine monophosphate

Both matter but neither should drive the decision on its own