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Several studies, both experimental and clinical, have demonstrated that the IGF-1R is overexpressed compared to normal tissues (Belfiore et al, 1999
T-RDN enhanced diuretic and natriuretic responses to GLP-1 in Sham + T-RDN group (urine flow at 20 min 106.5 16.2 vs
Numerous studies have investigated the expression patterns of endogenous GLP-1 and GLP-1R in the central nervous system (CNS) and the peripheral nervous system, with a consensus that these are expressed on neurons and found in most areas of the brain and gutbrain axis 2
Journal of Histochemistry and Cytochemistry, 61 , 649658
Using an inducible, epidermal-specific c-Jun/JunB double-knockout (DKO*) mouse model that faithfully recapitulates psoriatic skin and arthritis, the authors reveal profound metabolic alterations characterized by reductions in dermal fat and circulating free fatty acids, as well as elevated -hydroxybutyrate [3]
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