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Cohn JS, Patterson BW, Uffelman KD, Davignon J, Steiner G
Therapeutic implications: amplification vs containment The therapeutic implications of ferroptotic propagation are highly context-dependent
This vital recycling process is driven by an enzyme called glutathione reductase, which utilizes NADPH (a derivative of vitamin B3) to break the disulfide bond and regenerate two fresh, active GSH molecules
Okabayashi T et al
The significance of glutamate as an energy source is further discussed by Kreft et al
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