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Contraindications and Drug Interactions Absolute contraindications include Wilsons Disease or other copper metabolism disorders (risk of dangerous copper accumulation), known copper allergy or hypersensitivity (risk of severe allergic reactions), and pregnancy/breastfeeding (no safety data available for systemic use)

Polycystic ovary syndrome affects 7-10% of women of reproductive age

Hydration all day , because dehydration worsens constipation and dizziness

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see Vitamin B12 Health Professional Fact Sheet