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Elevated or dysregulated neuroinflammation leads to deleterious effects, including the release of cytotoxic cytokines, oxidative damage, and synaptic dysfunction, all of which exacerbate disease progression (141)

Research on Long-term Semaglutide Use Clinical trials have primarily focused on semaglutides efficacy and immediate side effects, with long-term studies still emerging

In addition to this, for a given amount of calories used during exercise, more calories will come from body fat if caffeine is consumed before exercise

This highlights why these drugs are generally considered long-term treatments for a chronic condition

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