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Alphafold3 36 predictions support a very similar OCTN1 sodium-binding site to OCTN2 (Supplementary Fig

There was no evidence demonstrating other significant safety issue differences (e.g., serious AEs) between GLP-1RA plus SGLT2i combination therapy and either GLP-1RA or SGLT2i monotherapy [59]

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No published trial has compared different KLOW cycle lengths