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Slowed Gastric Emptying: GLP-1 slows down the rate at which food leaves the stomach and enters the small intestine
Constipation may first appear during this phase
Mortality rate of RA patients declined significantly only a few years after the introduction of anti-TNFs in clinical practice [65], while recent data suggest that patients with RA, PsA and AxSpA exhibit comparable mortality rate with the general population the past 5 years before the COVID-19 pandemic [15]
Clemmons DR
The study showed that orforglipron led to significant weight changes in participants, especially at the highest dose
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