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However, severe abdominal pain, complete absence of bowel movements for more than a week, blood in stool, or signs of bowel obstruction (persistent vomiting, extreme bloating) require immediate medical evaluation and should be reported to your PlexusDx provider right away

The key takeaway is that dose increases typically bring temporary worsening, and the body generally adapts over time

Vincenti, M

(6) per-protocol analysis restricted to patients with 6 prescriptions of each agent (N = 5,752 per group)