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Thymalin has demonstrated antitumor effects in experiments on rats with transplanted sarcoma, with tumor growth arrested in nearly 80% of cases and regression observed in over half of the subjects

However, in a subanalysis of participants with low vitamin B 12 status at baseline (n= 101), the B-vitamin supplementation slowed the decline in bone mineral density (total hip and femoral neck but not lumbar spine) (116)

Large-scale, well-designed trials with proper randomization and blinding are needed to determine whether high-dose oral supplementation is as effective as intramuscular injection for increasing vitamin B 12 status and alleviating clinical symptoms of vitamin B 12 deficiency

doi: 10.1084/jem.20110698 21 WongAWXiaoJKemperDKilpatrickTJMurraySS

This will play an important role in reducing any risks associated with these foods or supplements