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PMID: 11 CoatesLCSorianoERCorpNBertheussenHCallis DuffinKCampanholoCBet al

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Digestive adjustments Beyond nausea, the starting dose can cause constipation, diarrhea, or alternating between the two

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Some tolerate escalation smoothly, while others require a slower approach

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The duration of the therapeutic response varies widely: a day or up to weeks

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10.1210/endocr/bqae165 4 BorensteinM.HedgesL

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