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Huang S, Ma S, Ning M, Yang W, Ye Y, Zhang L, et al
The Lancet, 368 (9548), 1696-1705
The subcutaneous route administration of ND0612 shows sustained levodopa plasma levels, thus offering continuous drug delivery
This pharmacokinetic profile is not influenced by gallbladder status
The oligomer was then diluted 1/24 with a solution of TRIS 10 mM pH 7.5 to afford a final concentration of 10 M and incubated at 37 C (8.3 L of the oligomer stock solution was diluted with 190 L of TRIS 10 mM pH 7.5 and 1.7 L of the pancreatin solution)
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