Still, major trials on two GLP-1 drugs (tirzepatide and semaglutide) offer some information about the impact of these medications on muscle loss, according to a 2025 analysis in Obesity Reviews
More than half of Americans (58%) say cost is the primary reason they would not use a GLP-1, even if it were recommended by a doctor
1-8 Recent European Society of Cardiology guidelines for the management of cardiovascular disease (CVD) in patients with diabetes state that GLP-1 RAs (lixisenatide, liraglutide, semaglutide, exenatide extended release [ER], dulaglutide, efpeglenatide) should be considered for glucose-lowering treatment in patients with T2D at risk of or with heart failure (HF
Dehydration can worsen both medication side effects and may affect kidney function, which is particularly important if you are taking antibiotics that are renally cleared
Semaglutide medications include Ozempic and Wegovy