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Below are some of the most common symptoms people report: Blue, red or purple squiggles in the legs Changes in skin color near the veins Cramping in the calf or thigh (often at night or when standing up suddenly) Dry skin above the affected vein Itching, burning or throbbing around the veins Pain, aching or a feeling of heaviness in the legs and feet Swollen ankles or feet Swollen, lumpy, twisted or bulging veins These symptoms often worsen in warm weather or after standing or sitting for long stretches
A Wide Range of Individual Outcomes Average figures can obscure a great deal
Can significant changes in diet or weight, such as in cases of eating disorders, cause a persons period to stop
Royal Society of Chemistry: 898944
AChEIs such as donepezil enhance cholinergic transmission and have been approved for the treatment of AD on the basis that they were found to delay the progression of cognitive decline in clinical trials
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