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These cholesterol reductions brought levels comparable to those seen in lean, healthy control mice, suggesting comprehensive metabolic normalization

on the contrary, the amount of the lipid peroxidation product malondialdehyde increased in the same tissue (Bosch-Morell et al., 2009, 2011) have confirmed significant increased levels of lipid peroxidation and marked decrease in GSH, superoxide dismutase and catalase activities in the sciatic nerve of rats which were given alcohol for 10 weeks

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Panagiotopoulos S, Kontogiannis V, Papageorgiou C

Patients start with a 2.5 mg dose for four weeks before increasing to 5 mg