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doi: 10.1007/s00787-019-01352-2 4

Do not use if safety seal on cap or printed inner seal is missing or broken

Produced primarily in the liver, its synthesis is upregulated by the growth hormone (GH)

Additionally, elevated levels of the plasma amino acid homocysteine can be a functional marker of folate, vitamin B12, or vitamin B6 deficiency, as all these vitamins are required to convert homocysteine into methionine