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In the interim, NICE-approved options for weight management in adults with obesity include: Orlistat (available on NHS prescription) Semaglutide 2.4 mg (Wegovy) , recommended by NICE in 2023 for use in specific patient groups (NICE technology appraisal TA875) Tirzepatide (Mounjaro) , which received NICE approval in 2024 for obesity management (NICE technology appraisal TA1026) [18] Patients seeking advice about weight management or blood pressure control should be directed to their GP in the first instance, who can assess eligibility for currently approved treatments and refer to specialist services where appropriate
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This is as high as most people will ever go on standard protocols
Since this 2012 publication, there has been very little new research into this question
Chronic conditions often require 6-12 weeks
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