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Modest appetite reduction (6-9% of reviews) A small percentage report decreased appetite for 3-5 days post-injection
It includes 1-5 intramuscular or subcutaneous injections of 1000 mcg crystalline cyanocobalamin daily, followed by oral doses of 1000-2000 mcg/day Parenteral administration should be reserved for those with significant neurological symptoms NICE guideline: Vitamin B 12 deficiency in over 16s: diagnosis and management: Malabsorption as the confirmed or suspected cause of vitamin B 12 deficiency: Offer replacement to people if: lifelong intramuscular vitamin B12 Autoimmune gastritis is the cause They have had a total gastrectomy They have had a complete terminal ileal resection If the person has a vitamin B 12 deficiency because of malabsorption that is not caused by autoimmune gastritis, or a total gastrectomy or complete terminal ileal resection (for example, malabsorption caused by coeliac disease, partial gastrectomy or some forms of bariatric surgery): Offer vitamin B 12 replacement and Consider intramuscular instead of
A complete blood count (FBC) reveals overall health markers and can identify anaemia, which affects approximately 25-30% of individuals experiencing hair loss [2]
When the anemia is severe and the red blood cell count is extremely low, blood transfusions may be necessary for the first couple of days until the vitamin B 12 injections begin working
Advanced protocols with the 60 mg vial Beyond standard titration, the 60 mg vial supports several advanced dosing strategies that smaller vials cannot practically accommodate
