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Given the absence of disease-modifying therapies that meaningfully slow disease progression, supportive care remains the mainstay of treatment for patients with ALS

Cell migration and wound-closure assays (such as scratch assays in fibroblast or endothelial cell cultures) are standard in vitro models for studying this combination's proposed tissue-repair pathway effects, typically comparing single-compound versus combined-compound treatment conditions

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In mild cases, conservative measures such as exercise, leg elevation, weight control, and wearing compression stockings are recommended