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Alzheimers Dement 2015

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We calibrate and validate the model with experimental data from control C3H mice and from the rd1 mouse model for the disease RP 37

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The GH/IGF-1 axis declines with age, and secretagogues can transiently raise it, but restoring a biomarker toward youthful levels has never been shown to equal restored youthful function and some GH-axis interventions carry theoretical risks that make the anti-aging framing particularly premature

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