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Methods We utilized cis-pQTL data from deCODE Genetics, combined with migraine GWAS data from the GERA + UKB cohort as the discovery cohort and the FinnGen R10 cohort as the replication cohort

An in vitro study

The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver (hepatocytes) and kidney (proximal tubules)

Once absorbed into the cells, it immediately goes to work donating electrons to unstable superoxide anions, hydroxyl radicals, and lipid peroxides

Complete medium was added to stop trypsin reaction and clumps of cells disrupted by pipetting