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8 Strengths and limitations The meta-analysis included a variety of research formats (RCTs, cohorts, casecontrol studies), offering a comprehensive perspective on the subject

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Post hoc Bonferroni analyses showed that weight loss was significantly greater with tirzepatide compared with both liraglutide (p = 0.001) and semaglutide (p = 0.014), and greater with semaglutide compared with liraglutide (p = 0.004)