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Alternatives are preferred, especially while nursing a newborn or premature infant
2011;2011(10):Cd006423
Now commercialized, these seven peptides have mostly been utilized for topical medications, though some have been injected into the body to treat severe bacterial infections
Subsequent studies demonstrated that apelin signaling is highly context dependent, with differential coupling to G_i, G_q, and -arrestin pathways depending on ligand structure, receptor density, and tissue environment (Murali and Aradhyam, 2023)
PMID 9072974
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