The receptor-binding region of human apolipoprotein E has direct anti-infective activity
They suggest that beyond weight loss, there may be biologic mechanisms at play whether through hormonal pathways, inflammation or direct effects on tumor biology that warrant further investigation. Important caveats and a path forward Despite the promising results, the authors emphasize that the study was observational and designed to assess short-term cancer incidence, not long-term prevention
Cawthon CR, Blonde GD, Nisi AV, Bloomston HM, Krubitski B, le Roux CW, Spector AC
Lots of factors are involved including monoamine imbalances, too little neurotrophic support, brain inflammation, and changes in how neurons connect with each other
Stress management and adequate sleep also support hormonal balance