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5 Two factors drive this gap: Early discontinuation: About 22 % of semaglutide users and 16% of tirzepatide users stopped treatment within the first year, and many more quit after the one-year mark

The drug also blocks the activin type II receptors on fat cells, and this action appears to reduce fat mass, says Steven Heymsfield, an obesity and body-composition expert at Pennington Biomedical Research Center in Louisiana

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When included as part of a holistic treatment plan, GLP-1 shots shows promise for both children and adults struggling with excess weight