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These drugs, derived from the hormone glucagon-like peptide-1, enhance insulin secretion, delay gastric emptying, reduce appetite, and promote weight loss [6]

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We demonstrated 28 that hepatocytes expressed the cognate HMGB1 receptors TLR2, TLR3, TLR4, and TLR9 allowing for a direct response to released HMGB1 and that HMGB1 by itself can induce cell death

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