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At 40 weeks, all three doses (3 mg, 12 mg, 36 mg) of orforglipron achieved the primary endpoint of superior A1C reduction compared to placebo , lowering A1C by 1.3% to 1.6% from a baseline of 8.0% , with improvements seen as early as 4 weeks

(Hammer Nutrition Direct, 2019)

Microchem J 187:108316 Acknowledgements The author, Harjeet thankfully acknowledges the Council of Scientific & Industrial Research, Government of India , through the CSIRUGC NET Junior Research Fellowship (JRF) as per grant ID E-Certificate No