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First described in the mid-1990s, it is classified as a growth hormone secretagogue (GHS), a category of compounds designed to interact with the ghrelin/GHS receptor

The sodium chloride can interfere with certain peptide structures

Wilcox et al., 2011)

Potential Side Effects Although both peptides are well-tolerated, some patients may experience: Mild water retention Joint stiffness (temporary) Insulin sensitivity changes (rare) Injection site irritation Patients should always be monitored by a physician trained in peptide therapy, and adjustments can be made to dose or frequency to mitigate any issues

For in vitro analysis, RAW264.7 macrophages and apoptotic Jurkat cells were cocultured under high glucose conditions (HG, 30 mM)