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Niswender K, Pi-Sunyer X, Buse J et al (2013) Weight change with liraglutide and comparator therapies: an analysis of seven phase 3 trials from the liraglutide diabetes development programme
Multiple factors drive this decline
These trials were randomized, double-blind, and placebo-controlled
Characterising how specific amino acid changes in variant receptors alter binding affinity, Gs coupling efficiency, cAMP signalling, and MITF activation in response to MC1R agonist stimulation
Weight loss of 12 pounds per week is considered safe and healthy
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