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Compared to the commercially available peptide Matrixyl 3000, GHK-Cu produced a 31.6% reduction in wrinkle volume

however, the results did not reach statistical significance (Figure 4)

identified one other host protein (TRMT1) that bound only to the inactive M pro C145A mutant, and concluded it was a likely M pro substrate, because they were able to identify a putative M pro cleavage site in the TRMT1 protein sequence (PRLQ/ANFT), where the slash (/) represents the cleavage site

Cooling Water Treatment Principles and Practice, Chemical Publishing Company, Inc., 1999