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The New England Journal of Medicine , 384(11), 989-1002
Biochem Pharmacol 34:11851189
Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function
Understanding these contributing mechanisms enables healthcare providers to implement targeted management strategies, optimize treatment tolerability, and distinguish medication-related fatigue from potentially serious underlying conditions requiring further evaluation
A Friday evening injection, for example, allows any initial nausea to resolve over the weekend
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