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This leads to neuroinflammation, vascular occlusion, mitochondrial dysfunction, and the aggregation of pathognomonic proteins, which, in turn, trigger neurodegeneration in the cerebral cortex for AD and the substantia nigra for PD (illustrated in Fig
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The base also features rubber feet for floor mounting, threaded sockets for coupler attachments, and built-in safety wire points
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Derangements in signaling can cause a persistent feeling of hunger, lack of satisfaction from normal amounts of food, and extremely strong cravings - all of which are often mistakenly associated with a lack of willpower
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