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Advances in redox-responsive drug delivery systems of tumor microenvironment

For example, damage-associated molecular patterns (DAMPs) or KRAS G12D proteins released from ferroptotic cells can be packaged into exosomes and internalized by macrophages, transforming them into the M2-like phenotype and leading to an immunosuppressive environment [118]

LPS-free indicates that the peptide has been tested to confirm the absence of lipopolysaccharides, which can interfere with experimental outcomes

The depletion problem Glutathione declines with age

BPC-157 helps restore these junctions by up-regulating occludin and claudin