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One of the major benefits of injectables compared to other treatments is that there is no downtime

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Semaglutide used for weight loss activates GLP-1 receptors in the body, leading to increased insulin secretion and reduced appetite

The headline On Thursday 21 May 2026, Eli Lilly announced that participants in TRIUMPH-1, the first Phase 3 trial of retatrutide in obesity, lost an average of 28.3% of their body weight at 80 weeks on the 12 mg dose, with 45.3% losing at least 30% of their starting weight [1]