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This could eventually help reduce reliance on biopsies, which are invasive and difficult to repeat, and make it easier for clinicians to monitor patients over time
10.1542/peds.2007-2361 82 KatoY.YokokuraM.IwabuchiT.MurayamaC.HaradaT.GotoT.et al (2023)
Metabolic adaptation is one: as you lose weight, your body requires fewer calories, so the same caloric deficit that produced weight loss initially no longer creates a meaningful gap
Drug makers are allowed to set prices hence the cost
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