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The American College of Gastroenterology guidelines for IBS management emphasize the importance of comprehensive medication counseling and established follow-up plans for patients with functional gastrointestinal disorders

The gradual increase allows receptor adaptation and gastrointestinal adjustment

2011 Oct;44(2):192-201

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While this approach ensured a comprehensive inclusion of relevant articles and provided a general overview of the role of GLP-1 in pain, it may have limited the depth of evidence on specific pain conditions