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9,474,780 (780) was filed in 2015 and is expected to expire in the U.S

From the anesthesiologist point of view, the growing number of patients treated with incretin-based therapies undergoing deep sedation and general anesthesia uncover the possible dark side of these drugs such as revealed by many case reports documenting the association between general anesthesia and gastric aspiration of a large amount of gastric content (including undigested food particles) in patients taking GLP1-RAs during the peri-operative period [10,11,12]

What remains unclear is whether patients taking GLP-1 RAs have an increased risk of aspiration

Results are expressed as means SEM

The aroma compounds released from heated food contribute to queasiness in sensitive individuals