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These hormonal shifts happen independently of weight loss, meaning metabolic benefits begin before visible fat loss occurs

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This article examines the practical considerations, technique, and evidence surrounding thigh versus stomach injections for Wegovy, providing guidance to help patients optimise their treatment experience

They may improve digestion and prevent constipation by supporting a healthy gut

In terms of ventricular load, SGLT2i reduce cardiac load via osmotic diuresis and enhance urinary sodium excretion while also decreasing arterial stiffness and improving endothelial function [109]