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The high capacity, low-affinity GLUT2 and high K M glucokinase (GK) in -cell ensure the proximal glucose-sensing

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Photo-oxidation is exacerbated during retinal degeneration and progressive loss of photoreceptors, as the choroid cannot alter the inflow of oxygen supply in response to the changing retinal environment, so the remaining photoreceptors become exposed to a higher oxygen level 22

34619776) If the level is below target, then an additional partial load may be administered