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Chronic gut permeability is where it becomes a problem LPS crossing into the bloodstream can get past the blood-brain barrier too When it does, it activates microglia (the brains immune cells) which start breaking down the blood-brain barrier
There is a reason they are almost always discussed as a pair
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It also depends on how deficient you are already
Your transition is motivated by either a weight loss plateau, a desire for the metabolic benefits of glucagon receptor activation, or both
