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Semaglutide reduced MACE incidence, with no heterogeneity in effect across baseline body habitus measures

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The effect is pharmacological (dependent on the presence of the drug) rather than structural (permanent changes to the heart)

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Conclusion Retatrutide is an exciting new option for weight loss

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New England Journal of Medicine , 384 (11), 9891002.

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Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1

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