The specific mechanism may involve a compromised intestinal barrier allowing antigens from the gut microbiota to penetrate and contact IgG antibodies, forming immune complexes that circulate in the bloodstream, including to the choroid plexus of the CNS
In turn, this may lead to vitamin B12 deficiency
Thyroid issues, anemia, or nutrient deficiencies can also show up this way, and it never hurts to rule those out
So its entirely reasonable to ask how drugs that enhance insulin action such as GLP-1 medications like semaglutide or tirzepatide can reduce harmful visceral fat, lower the risk of heart attack and stroke, and possibly even influence long-term cancer risk
In particular, studies have shown that carnitine supplementation is able to reduce post-exercise muscle stress (3-6)