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These rearrangements probably reduce the affinity of ABCB7 for CoPP, so priming the transporter for substrate release
The Gila monster is not the only reptile to inspire groundbreaking drugs
Individuals with defective carnitine transport have poor intestinal absorption of dietary L-carnitine, impaired L-carnitine reabsorption by the kidneys (i.e., increased urinary loss of L-carnitine), and defective L-carnitine uptake by muscles (4)
Activity 14 (1), 5973
B cell rich meningeal inflammation associates with increased spinal cord pathology in multiple sclerosis
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