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Tolerability and Safety Questions Both candidates are likely to be judged partly on gastrointestinal tolerability: nausea, vomiting, diarrhea, constipation, dose escalation, and discontinuation due to adverse events
As Healio previously reported, a study by Bian and colleagues published earlier this year showed older adults with cancer and type 2 diabetes who used GLP-1 receptor agonists exhibited significantly lower risk for all-cause mortality than those treated with dipeptidyl peptidase-4 inhibitors
How is gastritis diagnosed and treated
Arthralgia (joint pain) is listed as an adverse reaction in the UK Summaries of Product Characteristics (SmPCs) for approved incretin-based therapies
Research on GLP-1 discontinuation shows that most patients regain a significant portion of lost weight after stopping the medication, which means many patients need some form of ongoing treatment, often at a lower dose, to maintain results
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